A Studying the effectiveness of propolis against Salmonella abony and Candida albicans and identifying its active compounds

Section: Research Article

Abstract

Two samples of propolis were collected from Dohuk citie starting from October until the end of December (2023). The effectiveness of propolis was tested against the yeast Candida albicans ATCC 10231, and the bacteria Salmonella abony ATCC 6017. Propolis showed inhibitory activity against the isolates under study, as the growth inhibition rate of C. albicans reached 19.40% at a concentration of 600 mg/ml, while the growth inhibition rate of Salmonella abony reached 18.15% at the same concentration. The chemical compounds were detected by transient Thin Layer Chromatography (TLC), which showed that it contained Morin, Caffeic acid, Apigenin, Flavone, and Ferulic acid, other chemical compounds were also detected when analyzing the propolis sample using GC-MS technology, where it was noted that the most abundant compounds were: 2-Propen-1-one, 1-(2,6-dihydroxy-4,1,3-methoxyphenyl)-3-phenyl-, (E)- (27%), Oleic Acid (8.96%), and Phenylethyl Alcohol (6.95%).

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