The Effect of Environmental Pollution on Liver and Kidney Function of Individuals in Different Environmental Areas (Rural and Urban)

Section: Research Article
Issue
Vol. 2 No. 1 (2024): Journal of Rafidain Environment January 2024
Published
Oct 6, 2025
Pages
42-54

Abstract

     This study was conducted to investigate the effect of continuous exposure to environmental pollutants on the liver and kidney functions of individuals living in the city of Mosul (urban area) and Sheikhan district (rural area). In the current study, (80) blood samples were collected from males only, non-smokers, non-drinkers, and healthy individuals with chronic diseases, their ages ranged between (21-55) years. The samples were divided into two groups, where the first group included (40) blood samples from individuals from the city Mosul, while the second group included (40) blood samples for individuals from the Sheikhan district and the same age groups. Venous blood samples were collected at a rate of (4-6) ml from each person, taking into account the exclusion of any decomposing samples (Hemolysis) in order to exclude any false result.


      The results in this study showed that there was a significant increase in Alkaline Phosphatase (ALP) enzyme activity, Aspartate Transminase (AST) enzyme activity, The activity of Alanine Aminotransferase (ALT) enzyme, Urea concentration, Creatinine concentration and Glucose concentration in the group of males living in Mosul city compared with the group of males living in Sheikhan district.

References

  1. Al-Janabi, Munif Saab Ahmed., 2008. A physiological, biochemical and cellular study of the effect of a number of pollutants emitted in Baiji thermal power station on its workers. PhD thesis, College of Education, Tikrit University, Iraq, 63-72.
  2. Abdel Aziz, I.I. and Al Agha, S.Z., 2006. Hematological and Biochemical Studies for Gasoline Toxicity Among Gasoline Workers In Gaza Strip. Al-Aqsa University Journal (Natural Sciences Series), 10(SE), pp.41-58.
  3. Adamu, K.M. and Iloba, I.K., 2008. EffEcts of sublEthal concEntrations of Portland cEmEnt PowdEr in solution on thE aminotransfErasEs of thE african catfish (CLARIAS GARIEPINUS (burchEll, 1822)). Acta Zoologica Lituanica, 18(1), pp.50-54.
  4. Anyanwu, C.F., Aigbogun Jr, E.O. and Joseph, T.O., 2020. Evaluation of the liver enzyme (AST, ALT & ALP) levels of adult HIV patients on HAART in UPTH. Annual Research & Review in Biology, pp.34-41.
  5. Belfield, A. and Goldberg, D.M., 1971. Revised assay for serum phenyl phosphatase activity using 4-amino-antipyrine. Enzyme, 12(5), pp.561-573.
  6. D’Andrea, M.A. and Reddy, G.K., 2014. Hematological and hepatic alterations in nonsmoking residents exposed to benzene following a flaring incident at the British petroleum plant in Texas City. Environmental health, 13(1), pp.1-8.
  7. Elarabany, N.F. and El-Batrawy, O.A., 2019. Physiological changes in the Cattle Egret, Bubulcus ibis, as a bioindicator of air pollution in New Damietta City, Egypt. African Journal of Biological Sciences, 15(1), pp.13-31.
  8. El-Khayat, H.M., Hamid, H.A., Gaber, H.S., Mahmoud, K.M. and Flefel, H.E., 2015. Snails and fish as pollution biomarkers in Lake Manzala and laboratory A: Lake Manzala snails. Fisheries and Aquaculture Journal, 6(4), pp.1-9.
  9. Gavett, A.P. and Wakeley, J.S., 1986. Blood constituents and their relation to diet in urban and rural house sparrows. The Condor, 88(3), pp.279-284.
  10. Giansante, S., Giana, H.E., Fernandes, A.B. and Silveira Jr, L., 2022. Analytical performance of Raman spectroscopy in assaying biochemical components in human serum. Lasers in Medical Science, 37(1), pp.287-298.
  11. Guyton, A.C. and Hall, J.E., 2007. Buku ajar fisiologi kedokteran. EGC.
  12. H Jankeer, M., 2012. Effect of Lead on some Antioxidants and Lipid Peroxidation in Blood of White Male Albino Rats. Rafidain Journal of Science, 23(4), pp.55-69.Johnston, D.E., 1999. Special considerations in interpreting liver function tests. American family physician, 59(8), pp.2223-2230.Jude, A.C., Sasikala, K., Kumar, R.A., Sudha, S. and Raichel, J., 2002. Haematological and cytogenetic studies in workers occupationally exposed to cement dust. International Journal of human genetics, 2(2), pp.95-99.
  13. Hegazy, R.M. and Kamel, H.F., 2014. Oxidant hepatic &/or haem. Injury on fuel-station workers exposed to benzene vapor, possible protection of antioxidants. American Journal of Medicine and Medical Sciences, 4(2), pp.34-46.
  14. Hinton,P., 2004. “Statistics Explaned”.2nd ed. By Routledge. Printed in the USA and Canada, 85-125.
  15. Hussein, Mustafa Mahmoud Mustafa ., 2021. Industrial pollutants and their impact on environmental health in the urban community and a social field study in Damietta. Journal of the Faculty of Arts, Fayoum University, 13 (1), 3015-3102.
  16. Kales, S., Polyhronopoulos, G., Aldrich, J., Mendoza, P., Suh, J. and Christiani, D., 2001. Prospective study of hepatic, renal, and haematological surveillance in hazardous materials firefighters. Occupational and Environmental Medicine, 58(2), p.87.
  17. Khaki, Z., Amoli, J.S., Lesan, V. and Esfahani, T.A., 2011. Changes of serum biochemistry in short term toxicity with lindane pesticide in broiler chickens. Journal of Veterinary Research, 66(1), pp.1-81.
  18. L AL-Hayali, H., 2012. Effect of cement pollution on creatinine and blood urea in hamam al-alil factory workers. College Of Basic Education Research Journal, 11(3), pp.787-795.Moss, D.W.; Henderson, A.R.,1999 .Enzymes In Clinical Chemistry,2nd eds ,Philadelphia , pp 735
  19. Reitman, S. and Frankel, S., 1957. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. American journal of clinical pathology, 28(1), pp.56-63.
  20. Tietz, N.W., 1995. Clinical guide to laboratory tests. In Clinical guide to laboratory tests , pp. 1096-1096.
  21. Wilde, M., 2013. Civil Liability for Environmental Damage. Civil Liability for Environmental Damage, pp.1-360.
  22. Young, D.S., 2001. Effects of disease on Clinical Lab. Tests, 4th ed AACC, 25.
  23. Zahlouq, Amira Muhammad Abd al-Salam ., 2021. Environmental pollution and its effects on community health. Al-Qirtas Journal for Humanities and Applied Sciences, 15.
  24. Zaman, M.M., Choudhury, S.R., Ahmed, J., Talukder, M.H. and Rahman, A.S., 2016. Blood glucose and cholesterol levels in adult population of Bangladesh: results from STEPS 2006 survey. Indian Heart Journal, 68(1), pp.52-56.
  25. Zhang, L., Wang, F., Wang, L., Wang, W., Liu, B., Liu, J., Chen, M., He, Q., Liao, Y., Yu, X. and Chen, N., 2012. Prevalence of chronic kidney disease in China: a cross-sectional survey. The lancet, 379(9818), pp.815-822.

Authors

Raneen Mohammad Al-Shuraifi
Zahra Izideen Dallalbashi

Identifiers

https://doi.org/10.33899/jre.v2i1.49809
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